What is the current price and valuation for ISRG stock?

Pre-market on 27 Feb 2026 ISRG trades at **$506.88** on NASDAQ, with EPS **8.05** and PE **62.97**. Price/sales is **17.88** and price/book is **10.09**, indicating high growth expectations priced into the shares.

What catalysts could move ISRG stock higher?

Primary catalysts are stronger-than-expected da Vinci 5 placements, higher procedure utilization, expansion of Ion diagnostics, and AI-enabled workflow gains that raise recurring revenue and margins.

What downside risks should investors watch for with ISRG stock?

Key risks include international budget limits, tariff-driven margin erosion, Medicaid policy changes, intensifying competition in China, and any slowdown in hospital capital spending.

How does Meyka AI view ISRG and what is the forecast?

Meyka AI assigns ISRG a **79.80/100** (Grade B+, Suggestion: BUY) and forecasts a 12‑month price of **$602.22**, implying **18.82%** upside. Forecasts are model-based projections and not guarantees.

US Stocks

ISRG $506.88 Intuitive Surgical NASDAQ Pre-market Feb 2026: AI tailwinds

ByDanny Kontos February 27, 2026February 27, 2026

We open pre-market on 27 Feb 2026 with Intuitive Surgical, Inc. (ISRG) trading at $506.88 on the NASDAQ in the United States, driven by continued procedure growth and AI-enabled product momentum. ISRG stock shows volume 1,570,742 and a price-to-earnings ratio of 62.97 as investors weigh da Vinci 5 placements and Ion expansion. Today’s note connects recent analyst commentary, fresh institutional flows, and technicals to practical trade and portfolio questions for AI-focused investors.