$527.44 ISRG Intuitive Surgical (NASDAQ) Pre-Mkt Jan 21 2026: AI drives outlook
ISRG stock opens pre-market at $527.44 on 21 Jan 2026 as investors position ahead of Q4 results due 22 Jan 2026. The company trades on NASDAQ in the United States and shows volume 2,147,671 and a one-day decline of -1.41%. Market attention centers on continued adoption of the da Vinci 5 platform and early AI-enabled service features. We examine valuation, near-term catalysts, and what the Meyka AI model projects for price targets.
Price and key metrics for ISRG stock
Intuitive Surgical, Inc. (ISRG) is trading at $527.44 on NASDAQ with a market cap of $189.07B and shares outstanding 358,476,505. The stock opened at $527.00, with a day range of $525.23–$532.61, a 52-week range of $425.00–$616.00, and average volume 1,998,311. ISRG reports EPS 7.54 and a trailing P/E near 69.95, showing premium valuation versus peers in the Medical – Instruments & Supplies industry.
Earnings, catalysts and ISRG stock near-term drivers
Intuitive Surgical reports Q4 results on 22 Jan 2026 with an earnings announcement time listed as 16:00 ET. Recent preliminary commentary showed ~18% procedure growth and 532 system placements in the quarter, including 303 da Vinci 5 systems. Investors will watch system placements, instruments and accessories revenue per procedure, and tariff or pricing pressure in China as critical near-term drivers. For background reading see coverage from CNBC and a pre-Q4 note on Nasdaq.
Meyka AI rates ISRG with a score out of 100 and technicals for ISRG stock
Meyka AI rates ISRG with a score out of 100: 76.44 (Grade: B+, Suggestion: BUY). This grade factors in S&P 500 benchmark comparison, sector performance, financial growth, key metrics, and analyst consensus. Technical indicators show RSI 65.69, MACD histogram 0.11, ADX 22.53, and Bollinger middle band 566.22, suggesting positive momentum with near-term resistance around $590.15.
Valuation, ratios and ISRG stock forecast
ISRG is richly valued with price-to-sales 19.65, price-to-book 11.10, and EV/EBITDA roughly 51.95. Free cash flow per share is 6.37 and cash per share is 13.77, supporting capital flexibility despite premium multiples. Meyka AI’s forecast model projects a yearly target of $584.28 and a monthly target of $632.22. Versus the current price $527.44, the yearly target implies +10.78% upside and the monthly target implies +19.88% upside. Forecasts are model-based projections and not guarantees.
Risks, opportunities and ISRG stock outlook
Key risks include tariff headwinds, pricing pressure in China, and reimbursement changes for ambulatory settings. Opportunities include faster da Vinci 5 adoption, Ion platform expansion, and AI-enabled services that increase procedures and recurring revenue. Analysts show a mixed sentiment with 16 Buy, 3 Hold, and 2 Sell ratings in recent upgrade/downgrade data, reinforcing a cautiously optimistic consensus for ISRG stock.
Final Thoughts
ISRG stock trades at $527.44 pre-market on 21 Jan 2026 as the market waits for Q4 results and management commentary. Valuation remains elevated with trailing P/E near 69.95, but operating margins and cash metrics support reinvestment. Meyka AI’s forecast model projects $584.28 for the next 12 months, an implied upside of +10.78% from today. Short-term upside depends on reported procedure growth, system placements, and margin impact from tariffs. Long-term gains hinge on continued AI-driven service adoption and broader Ion platform traction. Our Meyka grade (B+, 76.44/100) reflects strong fundamentals and sector positioning, but it also flags valuation risk. Forecasts are model-based projections and not guarantees. Use earnings on 22 Jan 2026 as a decision point and weigh valuation against growth metrics before adding ISRG stock to a portfolio. Meyka AI provided the AI-powered market analysis used in this report.
FAQs
What is the current price and market cap of ISRG stock?
ISRG stock is at $527.44 pre-market on 21 Jan 2026 with a market cap of $189.07B and shares outstanding 358,476,505 in the United States (NASDAQ).
When will Intuitive Surgical report earnings and what matters?
Intuitive Surgical reports Q4 results on 22 Jan 2026 at 16:00 ET. Investors should watch procedure growth, system placements, I&A revenue per procedure, and tariff or pricing impacts.
What price targets and upside does Meyka AI show for ISRG stock?
Meyka AI’s forecast model projects a 12-month target of $584.28 (implied +10.78% upside) and a one-month target of $632.22 (implied +19.88%). Forecasts are model-based and not guarantees.
What is Meyka AI’s grade for ISRG stock and what it means?
Meyka AI rates ISRG 76.44/100 (Grade B+, Suggestion BUY). The grade combines benchmark, sector, financial growth, metrics, forecasts, and analyst consensus. This is informational, not investment advice.
Disclaimer:
Stock markets involve risks. This content is for informational purposes only. Past performance does not guarantee future results. Meyka AI PTY LTD provides market analysis and data insights, not financial advice. Always conduct your own research and consider consulting a licensed financial advisor.
