ISRG Intuitive Surgical NASDAQ pre-market Mar 23 2026: $479.93, Meyka B+ on AI

First up: ISRG stock opened pre-market at $479.93 on 23 Mar 2026, trading below its 50-day average and reflecting mixed sentiment around regulatory headlines and AI-driven robotics demand. Investors focus on near-term regulatory risk from stapler safety flags while analysts point to durable revenue growth and strong margins. The company reported recent quarterly EPS of $2.53 and trailing EPS of $7.87, supporting a premium valuation. We examine fundamentals, technicals, analyst price targets, and our AI-focused outlook for Intuitive Surgical, Inc. (NASDAQ: ISRG) in the United States market.